Biological effects of tremolite

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Association of Tremolite Habit with Biological Potential: Preliminary Report

Tremolite is an amphibole mineral which occurs naturally in three distinct mor­ phological forms or mineral habits. It may occur as asbestos, splintery fibres or in mas­ sive crystalline deposits. Mineral habit is determined at the time of its crystallization and conversion to a different habit would require re-crystallization. The massive crystalline deposits, on crushing may yield elongated f...

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Biologic Tests of Tremolite in Hamsters

Some years ago, we began to test specially prepared samples of minerals for carcinogenicity and fibrogenicity by intrapleural injection into hamsters. In these tests, we found that we could get tumors resembling mesotheliomas by injecting preparations of chrysotile asbestos fibers, provided that we used large enough doses, and provided that we used preparations with large numbers of fibers long...

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Mesothelioma in Cyprus: the role of tremolite.

There is a chrysotile mine in the central mountains of Cyprus but no other appreciable source of industrial asbestos. Hence the island was thought to offer ideal conditions to seek pure chrysotile induced mesothelioma. The first reported case was a village woman whose lung tissue contained amphibole asbestos fibres, which were later identified as tremolite. This began a search for the origin of...

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Chronic effects of dietary exposure to amosite asbestos and tremolite in F344 rats.

Carcinogenesis bioassays of blocky (nonfibrous) tremolite and amosite asbestos alone or in combination with the intestinal carcinogen 1,2-dimethylhydrazine dihydrochloride (DMH) were conducted with male and female Fischer 344 rats. The minerals were administered at a concentration of 1% in pelleted diet for the entire lifetime of the rats starting with the dams of the test animals. One group of...

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Infrared and TEM characterization of amphiboles synthesized near the tremolite-pargasite join in the ternary system tremolite-pargasite-cummingtonite

High-resolution transmission-electron microscopy (HRTEM) and infrared spectroscopy (FTIR) analyses have been done on amphiboles near the join tremolite [Ca2Mg5Si8O22(OH)2 = TR]-pargasite [NaCa2Mg4Al3Si6O22(OH)2 = PG] in the ternary system tremolite-pargasite-cummingtonite [Mg7Si8O22(OH)2 = MC] that were synthesized previously by Sharma and Jenkins (1999). Representative samples across the join ...

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ژورنال

عنوان ژورنال: British Journal of Cancer

سال: 1982

ISSN: 0007-0920,1532-1827

DOI: 10.1038/bjc.1982.61